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Name
Thorsten Hornemann
Title
Prof
Bio
Th. Hornemann is professor for clinical chemistry and head of research at the Institute for Clinical Chemistry, University Zurich. His primary interest is the sphingolipid metabolism. Prof. Hornemann and his team developed several unique analytical methods and metabolic labelling techniques to investigate the structure, function and metabolism of sphingolipids with a particular focus on rare and bioactive sphingolipid metabolites.
He discovered and characterized a class of atypical and toxic 1-deoxySphinglipids (1-deoxySL) as pathogenic metabolites causing the inherited peripheral neuropathy HSAN1 and also linked 1-deoxySLs to the pathology of the diabetic sensory neuropathy.
He has long-standing experiences in analytical chemistry and LC-HRMS-based lipidomics (targeted and untargeted) and established several lipid metabolites and lipid based metabolic signatures as diagnostic and prospective biomarkers for cardio-metabolic diseases - including NAFLD, CVD, MetS and T2DM.
He discovered and characterized a class of atypical and toxic 1-deoxySphinglipids (1-deoxySL) as pathogenic metabolites causing the inherited peripheral neuropathy HSAN1 and also linked 1-deoxySLs to the pathology of the diabetic sensory neuropathy.
He has long-standing experiences in analytical chemistry and LC-HRMS-based lipidomics (targeted and untargeted) and established several lipid metabolites and lipid based metabolic signatures as diagnostic and prospective biomarkers for cardio-metabolic diseases - including NAFLD, CVD, MetS and T2DM.
