Professor, PhD,
Medical University of Graz, Austria
Dagmar Kratky is Professor of Biochemistry at the Gottfried Schatz Research Center of the Medical University of Graz in Austria. She is a molecular biologist and biochemist with expertise in lipid and energy metabolism of mutant mouse models.
Storage and degradation of lipids are tightly regulated processes involving intracellular lipid hydrolases, enzymes of lipid biosynthesis, and regulatory proteins. Excessive lipid accumulation is central in the pathogenesis of prevalent metabolic diseases such as obesity, diabetes, and atherosclerosis. Her research interests focus on the role of lysosomal and cytosolic lipases in various cells and organs. The research group utilizes mutant mouse models with loss or overexpression of lipases to study the impact of the respective enzymes on whole-body lipid and energy metabolism. Over the past years, the laboratory has successfully explored the role of neutral and acid lipid hydrolases in tissues and various blood cell types including macrophages and neutrophils. The group aims to understand the molecular mechanisms that cause abnormalities in lipid and lipoprotein metabolism associated with the development of chronic inflammatory disorders including atherosclerosis. In addition, they are interested in cell and tissue autonomous functions of the respective enzymes.
Dagmar Kratky wants to pass on her enthusiasm for lipid metabolism by mentoring young scientists. Dagmar has broad leadership experience as board member of various scientific societies. She is currently treasurer of the European Lipoprotein Club, president elect of the Austrian Atherosclerosis Society and coordinates the excellent network program “SFB Lipid Hydrolysis” funded by the Austrian Science Fund (FWF).