Get an exclusive first look at BrainXell’s newly launched human iPSC-derived sensory neurons and learn how they enable reproducible, human-relevant models for sensory transduction, pharmacology, and ion channel research.
Be among the first to explore BrainXell’s recently launched human iPSC-derived sensory neurons and learn how this new platform is advancing human-relevant models for sensory biology research and drug discovery. Human sensory neuron models are increasingly essential for advancing translational neuroscience research, particularly in pain biology, sensory transduction, and ion channel pharmacology. Traditional model systems often lack human-specific biology or reproducibility at scale, limiting predictive insight during drug discovery workflows. BrainXell’s sensory neurons are designed to address these challenges through controlled differentiation, scalable manufacturing, and stringent quality control processes that support consistent experimental outcomes across studies.
In this webinar, BrainXell scientists will present comprehensive characterization data demonstrating neuronal maturation, robust marker expression, functional responsiveness to canonical agonists, electrophysiological activity, and pharmacological specificity. Attendees will gain insight into how these neurons support applications including sensory transduction studies, ion channel screening, and pharmacological validation using physiologically relevant human models. Functional responses to ATP, capsaicin, icilin, histamine, and thermal stimuli highlight the platform’s utility for discovery and translational research programs.
Key Topics:
- How human iPSC-derived sensory neurons mature post-thaw and develop functional neuronal networks within 3–4 weeks.
- Key marker expression profiles including NaV1.7, NaV1.8, NaV1.9 sodium channels and TRPV1/TRPM8 sensory transduction markers.
- How functional assays demonstrate pharmacological specificity through agonist and antagonist responses.
- Applications of electrophysiology and MEA readouts for evaluating neuronal activity and ion channel modulation.
- Best practices for integrating reproducible human sensory neuron models into screening and drug discovery workflows.