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Join us to explore how laser microdissection (LMD) connects selected tissue regions with downstream proteomic analysis.

Three researchers share complementary applications: investigating potential recurrence biomarkers in archival rectal cancer tissue; using Deep Visual Proteomics to compare tumour and host regions in primary and metastatic osteosarcoma; and examining antigen presentation in distinct regions of mouse spleen.

Hear practical insights into tissue selection, sample preparation and mass spectrometry workflows, and discover how LMD supports research into cancer biology and tissue immunology.

A 75-minute session featuring 15-minute presentations from each researcher, followed by an interactive Q&A and a brief demonstration from Leica.
Agenda
  • Learn how LMD isolates selected cells and tissue regions for downstream proteomic analysis.
  • How archival formalin-fixed paraffin-embedded (FFPE) rectal cancer tissue is being investigated for potential biomarkers of distant recurrence.
  • How an LMD-based Deep Visual Proteomics workflow compares tumour and host regions, including primary and metastatic osteosarcoma tissue.
  • How spatial immunopeptidomics links antigen presentation profiles to defined anatomical regions of mouse spleen.
  • Practical considerations for tissue preparation, region selection and integrating LMD with mass spectrometry workflows

Hosted By Leica Microsystems
Featured Presenters
  • Webinar hosting presenter

    Vo Van Anh Pham (Anh)

    Laser Microdissection Enables Deep Proteomic Profiling of Archival Rectal Cancer Tissue
    Vo Van Anh Pham (Anh) is a PhD candidate in the Bowel Cancer and Biomarker Research Group, supervised by Professor Mark Molloy. Her Honours project focused on identifying proteomic biomarkers that predict distant recurrence in early-stage rectal...
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  • Webinar hosting presenter

    Mohammad Javadzadeh

    Spatial immunopeptidomics enabled by Leica laser microdissection
    Mohammad Javadzadeh is a third-year PhD candidate in the Purcell laboratory at Monash University’s Biomedicine Discovery Institute. He holds a bachelor’s degree in Medical Laboratory Sciences and a master’s degree in Medical Immunology. His PhD...
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  • Webinar hosting presenter

    Sara M. Osorio Quinones

    Deep Visual Proteomics captures spatial tumour-host identity and resolves distinct primary and metastatic proteomic states in osteosarcoma
    Sara M. Osorio Quinones
    Technical Assistant, Monash Proteomics and Metabolomics Platform, Monash University

    Sara recently completed a Master of Biotechnology at Monash University, focusing on developing and optimising Deep Visual Proteomics...
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