The presentation will explore how environmental exposures and nutrition create heritable methylation marks that influence metabolic health across generations.
Through landmark studies including the Agouti mice experiments and Dutch Hunger Winter we will examine how methylation acts as both a vulnerability and protective mechanism, offering practical strategies for optimizing metabolic health from preconception through healthy aging.
AGENDA
The Three Pillars of Inheritance - DNA sequence (the Code), Methylation marks (the Switches), and Mitochondrial DNA
Landmarks studies: i) Agouti Mice - BPA exposure, the melanocortin system, AgRP connection, and how methyl-donor nutrients protect against obesity ii) Dutch Hunger Winter - Lasting health impacts of famine across generations through altered DNA methylation patterns
Personalized Nutrition and Lifestyle - Why one size doesn't fit all (MTHFR, genetic variants). Pro-methylation nutrients vs. anti-methylation toxins. Critical windows from preconception through healthy aging.
ADDITIONAL INFO
When:
Thursday, January 29, 2026 · 12:00 p.m.
London
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