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Join us to explore how laser microdissection (LMD) connects selected tissue regions with downstream proteomic analysis.

Three researchers share complementary applications: investigating potential recurrence biomarkers in archival rectal cancer tissue; using Deep Visual Proteomics to compare tumour and host regions in primary and metastatic osteosarcoma; and examining antigen presentation in distinct regions of mouse spleen.

Hear practical insights into tissue selection, sample preparation and mass spectrometry workflows, and discover how LMD supports research into cancer biology and tissue immunology.

A 75-minute session featuring 15-minute presentations from each researcher, followed by an interactive Q&A and a brief demonstration from Leica.
Agenda
  • Learn how LMD isolates selected cells and tissue regions for downstream proteomic analysis.
  • How archival formalin-fixed paraffin-embedded (FFPE) rectal cancer tissue is being investigated for potential biomarkers of distant recurrence.
  • How an LMD-based Deep Visual Proteomics workflow compares tumour and host regions, including primary and metastatic osteosarcoma tissue.
  • How spatial immunopeptidomics links antigen presentation profiles to defined anatomical regions of mouse spleen.
  • Practical considerations for tissue preparation, region selection and integrating LMD with mass spectrometry workflows

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