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High content image-based approaches yield rich phenotypic data that can reveal important insights into a candidate drug’s mechanism of action or toxicity. Cell Painting is an example of such a phenotypic assay.
Spearheaded by the Broad Institute,...
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    Monday, December 12, 2022 · 6:00 PM CET
    Choanoflagellates are the closest living relatives of animals. These single-celled protists express diverse animal genes, such as kinases, and are therefore a compelling system for studying ancestral functions of animal gene families. The emergenc...
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    Tuesday, November 15, 2022 · 5:00 PM CET
    The Joint Undertaking in Morphological Profiling (JUMP) Cell Painting (CP) Consortium, spearheaded by the Broad Institute, was established to generate a large public reference Cell Painting dataset. Scheduled to be released on Nov 1st, 2022, this ...
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    Tuesday, May 10, 2022 · 4:00 PM CEST
    Drug discovery is a time-consuming and costly process. The majority of promising pre-clinical drug candidates eventually fail in clinical trials, due to poor efficacy or toxicity issues. Considerable efforts are therefore directed toward the devel...
  • Tuesday, July 6, 2021 · 6:00 PM CEST
    Jonathan Sexton from the University of Michigan will show how he has used advanced phenotypic methods that incorporate automated microscopy, high content image analysis, and artificial intelligence for the development of a novel drug discovery pla...
David Egan's webinars