In this webinar, Radleys’ Ben Jeffery and Heidolph’s Kevin Berens discuss how to achieve reliable scale-up of in vitro transcription, from discovery through to GMP production. They explore the most common causes of batch failure, including contamination, poor temperature control and inconsistent stirring, and explain how Radleys’ reactor systems and AVA software provide reproducibility, flexibility and robust data logging. Real-world examples and live demonstrations show how the Mya 4 and Reactor-Ready systems support efficient cleaning, consistent process control and seamless progression from R&D to production.