Professor John O'Brien, Prof Craig Ritchie and Prof Iracema Leroi will discuss current perspectives on 3 classic dementias papers from across the decades.

• What did the paper tell us?
• Why is it a classic?
• What have we learned since then that has altered our practice?
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    John O'Brien
    Professor of Old Age Psychiatry, Department of Psychiatry, University of Cambridge
    Professor John T O’Brien is Professor of Old Age Psychiatry in the Department of Psychiatry at the University of Cambridge and Honorary Consultant Old Age Psychiatrist within Cambridgeshire and Peterborough NHS Trust and Cambridge University Hospitals NHS Trust. He is also a National Institute for Health Research Emeritus Senior Investigator and a fellow of the UK Academy of Medical Sciences.

    His research interests include: the application of neuroimaging in old age psychiatry; dementia with Lewy bodies; the role of vascular factors in dementia and depression and clinical trials. He has published over 500 peer-reviewed papers on these topics and is a member of the National Institute for Health and Clinical Excellence (NICE), British Association of Psychopharmacology and the European Federation of Neurological Sciences (EFNS) Dementia Guideline groups. He is past President of the International College for Geriatric Psychoneuropharmacology (ICGP) and a recipient of the Royal College of Psychiatrists Lifetime Achievement award in Older People’s Mental Health.

    His other current roles include being the NIHR National Specialty Lead for Dementia and Treasurer of the International Vas-Cog Society.
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    Professor Craig Ritchie
    Professor of the Psychiatry of Ageing, University of Edinburgh
    Prof Craig Ritchie is the Professor of Psychiatry of Ageing at the University of Edinburgh and Director of Brain Health Scotland.

    His academic interest is in the earliest stages of neurodegenerative disease and how they can be detected and managed to prevent dementia. He has run two international’s cohorts (EPAD and PREVENT) to generate the necessary data for this work. He has also been Chief Investigator on peer 30 clinical trials of drugs and biological agents to treat Alzheimer’s disease.

    He has over 300 academic publications and led the first Massive Open Online Course (MOOC) titled: Understanding Brain Health: Preventing Dementia. He is also the Chair of the Scottish Dementia Research Consortium.
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    Professor Iracema Leroi
    Associate Professor of Geriatric Psychiatry, Global Brain Health Institute, Trinity College Dublin
    Iracema is an Associate Professor of Geriatric Psychiatry at Trinity College Dublin and a Consultant Psychiatrist in St. James’s Hospital, Dublin. Iracema spent four years with the Neuropsychiatry and Memory Group at Johns Hopkins, Baltimore before moving to the UK in 2002. In 2017 she was appointed Professor of Psychiatry in Ageing and Dementia at the University of Manchester.

    She moved to Dublin in 2019 to join the Global Brain Health Institute (www.gbhi.org), a joint program between Trinity College Dublin and the University of California San Francisco. Iracema has a particular interest in the neuropsychiatry of neurodegenerative movement disorders including Parkinson’s disease. She recently completed the world’s largest RCT of a non-pharmacological intervention for people with Lewy body dementias (LBDs; the INVEST project).

    She developed and led the Greater Manchester clinical trials’ program for dementia for several years as principal investigator, and is Chief Investigator for EU-funded SENSE-Cog (www.sense-cog.eu), a five-year program involving 27 investigators researching the links among hearing, vision and cognitive impairment.

    She is also building collaborations for dementia research in Bangladesh, Pakistan and India and is leading the ‘Research Roadmap for Dementia in Pakistan’ project, which is model for lower and middle-income countries (LMIC).