The blood-brain barrier poses a unique challenge to pharmacologists and physicians. While it is effective at preventing circulating blood from entering the extracellular fluid of the central nervous system, it also prevents the delivery of potentially life-saving therapeutics to injured and diseased brains. Scientists are developing new drug delivery systems to circumvent these pharmaceutical challenges. This webinar will discuss new drug delivery approaches to overcoming the blood-brain barrier.

Topics to be covered

-Blood-brain barrier pathophysiology-independent drug delivery in traumatic brain injury
-Phage mimetics: Brain targeting made simple

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    Drug Discovery News Webinars
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    Nitin Joshi, M.Tech, PhD
    Instructor of Anesthesia, Center for Nanomedicine Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School
    Nitin Joshi is an instructor of anesthesia at Harvard Medical School and an associate bioengineer in the Department of Anesthesiology, Perioperative and Pain Medicine at the Brigham and Women’s Hospital. He obtained his PhD degree in biomedical engineering from the Indian Institute of Technology in Bombay, India, and completed a postdoctoral fellowship at the Brigham and Women’s Hospital. Joshi investigates drug delivery and biomaterials. His research has resulted in more than 10 granted and pending patents and technology disclosures, with most licensed to biotech companies and one advancing through clinical trials. Joshi’s research has been published in top-tier journals, including Nature Communications, Science Advances, Nanotoday, Biomaterials, and Journal of Controlled Release,. He has received multiple awards for his work, including MIT’s Technology Review Magazine (TR35) India Award, the Lockheed Martin Innovation Award, and the Boston Patent Law Association (BPLA) 2020 Invented Here! Featured Honoree Award. Joshi is passionate about training and mentoring the next generation of biomedical scientists and has mentored more than 30 students.
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    S. Moein Moghimi, PhD
    Professor of Nanomedicine and Pharmaceutics, School of Pharmacy, and Translational and Clinical Research Institute, Newcastle University
    Moein Moghimi is a professor of pharmaceutics and nanomedicine with the School of Pharmacy and an affiliated professor with the Translational and Clinical Research Institute at Newcastle University. He also serves as an adjoint professor at the Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, and Pharmaceutical Sciences at the University of Colorado-Denver Medical Center. Moghimi is a co-founder and advisory board member of S. M. Discovery Group Inc. (USA) and S. M. Discovery Group Ltd (UK). His research focuses on the fundamental and translational aspects of nanomedicine engineering and performance, with the overall goal of understanding of biological barriers to nanoparticle performance and safety within the context of precision medicine. Moghimi authored greater than 300 research papers, reviews, book chapters, patents, and patent applications. He is currently the associate editor of Molecular Therapy and Editor-in-Chief of the Journal of Nanotheranostics.