Scientists working in gene therapy introduce functional copies of genes to compensate for abnormal disease-associated genes. Gene therapy holds promise for treating a variety of inherited genetic disorders. New gene therapy advances combine regenerative approaches. This webinar will present some of the latest advances in gene therapy.
Topics to be covered
-Lentivirus-mediated gene therapy for Fabry disease
-Combining stem cell and gene therapy to mitigate Huntington’s disease symptoms
Dwayne L. Barber, PhD
Scientist, Princess Margaret Cancer Centre, University Health Network, Professor, Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto
Dwayne Barber is a scientist at Princess Margaret Cancer Centre and a professor in the Department of Laboratory Medicine and Pathobiology in the Temerty Faculty of Medicine at the University of Toronto. He studies signaling pathways in normal and leukemogenic hematopoiesis. Since 2013, he has translated this research into early phase clinical trials. He is currently responsible for two clinical trials: one that studies interleukin-12 to treat relapsed acute myeloid leukemia and a multi-center trial that utilizes lentiviral-mediated gene therapy to treat Fabry disease, a lysosomal storage disorder.
In Ki Cho, MS, PhD
Postdoctoral Fellow, Easley Lab, Regenerative Bioscience Center, Department of Environmental Health Science, University of Georgia
In Ki Cho received his BS in cell and molecular biology and MS in environmental and biological sciences with a concentration in toxicology from Troy University. He received his PhD in genetics and molecular biology from Emory University under the mentorship of Anthony W.S. Chan and Hui Mao. He completed postdoctoral training in stem cell biology, neuroscience, and developmental biology at Yerkes National Primate Research Center at Emory University, where he developed new research approaches for treating Huntington’s disease. In January 2021, Cho transitioned to a postdoctoral fellowship in the laboratory of Charles Easley at the University of Georgia. Cho’s research interests include regenerative medicine, stem cell and gene therapy, organoids, therapeutic discovery, biomarker discovery, aging, in vitro disease modeling, neurodegenerative diseases, trinucleotide repeat disorders, and environmental toxicology.