Join Dr. Martin Stahl in this webinar as he explores why understanding the cellular composition of your organoids matters–whether they are fully differentiated, missing rare-but-critical cell populations, or lacking key intestinal cell types. Using insights from recent research, he’ll demonstrate how differentiated cell states can alter drug response and toxicity readouts, potentially affecting the conclusions you draw from your studies.
Discover how IntestiCult™ Plus, a new, next-generation intestinal organoid growth medium, is designed to improve the balance of cell types within intestinal organoids. With the ability to support both expansion and differentiation within a single medium, IntestiCult™ Plus enables researchers to develop intestinal organoids that more accurately model the human intestinal epithelium, including improved representation of enteroendocrine cells, paneth cells, tuft cells, mature enterocytes, and other key cell populations.
Join us to learn how optimizing your organoid culture system can enhance your research in drug discovery, infection modeling, and beyond.
Key Topics:
- Learn how experimental outcomes are impacted by the proliferative versus differentiated state of your intestinal organoids.
- Understand the limitations of current intestinal organoid culture methods, including the trade-offs between expansion and differentiation, and how these factors influence the physiological relevance of your model.
- Discover how a next-generation intestinal organoid culture medium enables balanced expansion and differentiation, helping you generate organoid models that more accurately represent the human intestinal epithelium.
- Gain practical insights into evaluating and refining your intestinal organoid models to ensure they align with your specific research questions and experimental needs.