Webinar: High‑Throughput RT‑qPCR and Transcriptomics: Powering the Next Generation of Drug Discovery by InsideScientific

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High‑Throughput RT‑qPCR and Transcriptomics: Powering the Next Generation of Drug Discovery

About

Innovative mRNA modulating strategies are creating fresh opportunities for tackling hard-to-drug diseases.

In this webinar, experts Dr. Timur Samatov and Dr. Xavier Maréchal demonstrate how Evotec’s high-throughput RT-qPCR and ScreenSeq™ transcriptomics platforms drive these mRNA focused approaches – delivering rapid, scalable, and multidimensional insights.

Join us to see how a fully transcriptomics enabled workflow can advance mRNA driven discovery and speed progression from screening to candidate nomination.

What You'll Learn:

Explore why mRNA modulating strategies are expanding therapeutic possibilities

See how high-throughput, multiplexed RT-qPCR enables rapid screening of up to 13,000 compounds per day

Discover how unbiased, multidimensional transcriptomics accelerates hit validation, hit expansion, and SAR - perfectly complementing RT-qPCR data

Presenters

Timur Samatov, PhD

Group Leader, Transcriptomics

Timur Samatov, is a molecular biologist with a groundbreaking academic background. Getting his PhD from Moscow State University in 2006, he developed a pioneering cell-free genetic display technology. His postdoctoral work at the Max Planck Institute for Biophysical Chemistry focused on pre-mRNA splicing, where he developed high-throughput assays and conducted large-scale screens for splicing inhibitors.

Joining Evotec in 2016, Timur now leads a team driving high-throughput and high-resolution transcriptomics. As a Group Leader, he ensures team efficiency, individual growth, and a conducive work environment. Timur, an expert in transcriptomics, engages in strategic discussions with partners, defining support avenues and articulating data value.

Timur's team plays a crucial role in diverse disease-centric projects, actively progressing toward impactful medicines and therapies.

Xavier Maréchal, PhD

Research Scientist, High Throughput Screening and Biology

Xavier Maréchal is a biochemist specializing in enzymology and RT‑qPCR. He earned his PhD from the University Pierre et Marie Curie in Paris in 2011. During his doctoral training and subsequent postdoctoral positions at the Institut Pasteur de Lille and the CEA (Commissariat à l'Énergie Atomique et aux Énergies Alternatives), he focused on drug discovery, developing high‑throughput screening (HTS) assays, running HTS campaigns, and evaluating compounds throughout the hit‑to‑lead process in close collaboration with medicinal chemists.

Xavier joined Evotec in 2018, where he further specialized in the design and optimization of RT‑qPCR‑based HTS approaches for the identification of gene expression and mRNA splicing modulators. He now serves as a Team Leader within the High Throughput Screening and Biology department.

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