About
Complex biological processes, such as the transport of molecules across cell membranes, are difficult to understand using purely biological methodologies. Investigating cellular transport processes is challenging, because of the highly complex chemical composition of cells and the diffusion of molecules in and around cells at low concentrations. The development and advancement of electroanalytical methods over the last two decades has enabled the monitoring of living cells and their interaction with the environment, including external stimuli, such as pharma-molecules.

This presentation emphasizes electrochemical and electrophysiological methods of detection and quantification but will also make a comparison to other bioanalytical approaches. Join us to discover a substantial diversity in methods used to monitor the transport of cell metabolites, crucial for cell survival, and pharmaceutical compounds, involved in cell characteristics such as drug resistance.

Key Topics Include:
  • Understanding transmembrane molecule transport through bioanalytical methods

  • Electrochemical approaches to monitor molecule transport across cell membranes

  • What bioanalytical and especially electrochemical approaches can reveal

  • Challenges associated with instrument limitations
Presenter
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Sabine Kuss, PhD
Associate Head - Graduate Studies, Associate Professor, University of Manitoba
Dr. Sabine Kuss is Associate Head of Graduate Studies and Associate Professor in the Department of Chemistry at the University of Manitoba. She is an interdisciplinary scientist, and her research specializes in the electrochemical recognition of transmembrane molecule transport in living biological systems. As a bioanalytical electrochemist, her research team investigates endocrinological diseases, mitochondrial dysfunctions, drug resistance in bacteria and cancer, cancer development, and the development of electrochemical biosensors.

During her academic career she completed her undergraduate studies in Biology at the University of Technology Dresden, Germany, followed by an M.Sc. degree in Biochemistry at the Université du Québec à Montréal. Dr Kuss received a Ph.D. degree in Chemistry at McGill University in 2015 and took the opportunity to work as a Marie Curie European Postdoctoral Fellow at the University of Oxford, England. In 2019, Sabine was awarded the Early Career Analytical Electrochemistry Prize by the International Society of Electrochemistry. In 2022, Sabine received a Falconer Emerging Researcher Rh Award for Outstanding Contributions to Scholarship and Research, and she is a 2022 Canada’s Most Powerful Women: Top 100 Award Winner.
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