Watch Dr. Sarah Greising discuss the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.

Volumetric muscle loss (VML) injuries result in the abrupt loss of skeletal muscle fibers, causing chronic functional disability in part due to limited muscle regeneration and vast co-morbidities. With a focus on clinically relevant outcome measurements for skeletal muscle function in both small and large animal models of VML injury, this webinar covers various near-term interventions for the restoration of tissue function following complex injuries. Interventions evaluated focus on regenerative rehabilitation approaches using regenerative pharmaceuticals to correct underlying muscle pathophysiology.

Key Topics:

  • Understand the pathophysiologic limitations of volumetric muscle loss injuries

  • Appreciate the importance and necessity of evaluating treatment strategies in large animal models of injury for translational purposes

  • Understand the tools used to evaluate in vivo torque

  • Understand how data on a primary function of muscle can be transformative across species and fields

Sarah Greising, PhD
Associate Professor, Kinesiology, University of Minnesota
Sarah Greising, PhD, is an Associate Professor at the University of Minnesota. Her research focus and lab’s work is on conditions of skeletal muscle that have altered plasticity and/or limited to no regenerative potential, such as injury, aging, and disease.
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