Discover the impact of cryopreservation of PBMCs on T cell activation and phenotype in Lonza’s free webinar.
Human peripheral blood mononuclear cells (PBMCs) consisting of lymphocytes, dendritic cells and monocytes play an important role in both innate and adaptive immune systems. As such, PBMCs are increasingly being used in the drug development of biological therapeutics. Should you be concerned how cryopreservation will affect the various sub-populations of immune cells contained in your PBMC sample or performance parameters of those cells? Are you looking for more convenience in your immunology research workflows? Lonza scientists investigated what possible effects cryopreservation could have on the functionality of PBMC samples.
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In this webinar, you will learn about:
- T cell proliferative response is not altered by cryopreservation
- Cryopreservation does not change pro- or anti-inflammatory cytokines secretion profiles
- Cryopreservation does not alter the percentages of cell populations in PBMCs
- The data supports the more convenient use of cryopreserved PBMCs over freshly isolated cells