Digital twins and artificial intelligence are transforming how RF and microwave systems are designed, tested, and maintained. This panel brings together industry experts to explore how physics-based modeling combined with AI-driven analytics is enabling more accurate virtual prototypes, faster design cycles, and predictive performance insights across complex environments. Topics will include the integration of simulation and measurement data, real-time system optimization, and the role of digital twins in mission-critical applications such as aerospace, defense, and next-generation communications.