About
Join our webinar to discover how our iPSC-derived neuronal-glia co-culture system can advance your neurodegenerative disease research!

The central nervous system (CNS) consists of neurons and glia, including microglia and astrocytes. When astrocytes are activated by microglia, they transition into a neurotoxic state, leading to the death of neurons in neurodegenerative diseases. Thus, glial cells provide promising targets for novel drug development and play a crucial role in understanding the appropriate responses of neurons in an environment that closely mimics in vivo conditions.

To accelerate drug development for neurodegenerative diseases, FUJIFILM offers assays and disease modeling by leveraging its expertise with iPSC-derived cell handling technologies. This includes technologies such as neuron-glia co-cultures, based on FUJIFILM’s experience in drug development within the field of neurology.

Key Topics Include:

  • Learn about species differences in cytokine response between rodents and human astrocytes, highlighting the significance of utilizing human iPSC-derived cells

  • Recognize the importance of using iPSC-derived cells with aged features to recapitulate neurodegenerative diseases in vitro

  • Explore the potential of drug screening using neuron-glia co-cultures

  • Understand how our platform technologies can be harnessed for disease modeling and drug development purposes

Presenter
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Setsu Endoh-Yamagami, PhD
Senior Scientist and Manager, Bio Science and Engineering Laboratories, FUJIFILM Corporation
Dr. Endoh-Yamagami, a senior scientist at FUJIFILM, leads the iPSC-Neuropharmacology team. With Ph.D. from the Univ. of Tokyo in life sciences, she conducted postdoc research in the US at academia and biotech. At FUJIFILM, she has led neurodegenerative drug development and now focuses on drug discovery research services.
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