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At what level does an increased ALT or ALP unequivocally indicate liver disease? When are bile acids useful and when are they not? What does a positive PLI really mean? Do the results mean the same in dogs and cats – if not, why not?

Liver and pancreatic enzymes and other diagnostic parameters used to assess the hepatobiliary system are commonly measured by veterinarians on unwell patients, prior to anaesthesia or as a general metabolic profile for geriatric animals. Yet deciding exactly what the results mean and what they confirm or rule out can be difficult. During this lecture, I will discuss my top tips for interpreting clin path results related to the liver and pancreas focusing in particular on differences between cats and dogs.

The learning outcomes for this lecture will include:
  • To understand how to interpret liver enzymes and what mild, moderate and marked increases mean

  • To appreciate when bile acids useful and when are they not

  • To learn what a positive pancreatic lipase immunoreactivity (PLI) result really means in dogs and cats

  • To understand why liver and pancreatic clinical pathology results differ in dogs vs cats

  • 1590869161-89a22cb503e42ef3
    Professor of General Practice, Royal Veterinary College London
    Jill is currently a Professor of General Practice at the Royal Veterinary College (RVC) in the United Kingdom. She is the senior editor of Small Animal Clinical Pharmacology, the 2nd edition of which was published by Elsevier in 2008. She is also the senior editor of Clinical Reasoning in Small Animal Practice published by Wiley-Blackwell in April 2015. And 2nd edition will be published in 2022. Jill is the coordinator for the main small animal clinical CPD streams at The London Vet Show and Singapore Vet. To keep in touch with the realities of private general practice she regularly consults at a local veterinary practice and at the RVC’s first opinion practice, the Beaumont Sainsbury Animal Hospital.