During this webinar the diversity of various light scattering techniques for characterizing a wide range of protein samples and their applicability in pharmaceutical research will be shared.

We will start by highlighting the potential of dynamic light scattering (DLS) as a tool for rapid and straightforward aggregate detection, as well as its value in executing extensive formulation studies and predicting stability.

This will be followed by applications of multi-angle light scattering (SEC-MALS and FFF-MALS), showcasing its ability to provide absolute molecular weight, oligomerization, and conjugate analyses.

We will conclude with an introduction to real-time MALS, offering real-time insights and enabling direct process influence on attributes such as molar mass, size, and particle concentration.

Key Learning Objectives:

> Learn about the many ways light scattering detection can be used to characterize proteins, peptides, and protein conjugates.
> Introduction to Dynamic Light Scattering (DLS) for aggregate detection, formulation screening and stability prediction.
> Multi-Angle Light Scattering coupled to Size Exclusion Chromatography (SEC-MALS) for determination of the molar mass distribution of protein samples, to gain insights into the oligomeric state, and to characterize conjugated samples.
> Explanation of of Flow Field-Flow Fractionation coupled to Multi-Angle Light Scattering as an orthogonal method to SEC-MALS.
> Introduction to Real-Time MALS for process development and manufacturing.

Who Should Attend this Webinar?

Scientists working in the field of protein characterization, protein formulation and process development.