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WEBINAR ENDED
· 30 minutes

FEATURED PRESENTATION: Immune Mitigation Strategies to Prevent or Overcome Anti-AAV Abs and Enable AAV-Based Gene Therapy Dosing

Thursday, October 21, 2021 · 8:00 a.m. · Eastern Time (US & Canada)
About This Webinar

I will discuss the potential impact of pre-existing immunity on the efficacy of AAV-based gene therapy and provide a brief overview of mitigation strategies. Additionally, I will present preliminary non-clinical data from a few approaches we have evaluated aiming to remove existing antibodies or prevent the development of treatment-induced antibodies.

Who can view: Everyone
Webinar Price: Free
Featured Presenters
Webinar hosting presenter
Senior Director
Soumi Gupta received her Ph.D. in Microbiology from University of California, Davis in 2003, where the focus of her research was aimed at furthering our understanding of the immune correlates of protection towards a successful AIDS vaccine. She pursued post-doctoral training in Immunology at Chiron Corporation where she investigated anti-HIV T and B cell-mediated responses following mucosal immunization with alphavirus-based replicon particles encoding for HIV-Gag, Pol and Env. Following her post-doctoral training, she worked at Monogram Biosciences as a scientist in research and development, developing assays to characterize genotypic and phenotypic resistance to HIV antivirals. Soumi joined BioMarin in February of 2015 as a Director in Immunogenicity Assessment where she provides immunologic expertise to drug programs across developmental stages and develops immunogenicity and safety strategies for novel biologic therapeutics, including enzyme substitution therapies and AAV-mediated gene therapies.
Hosted By
Cambridge Innovation Institute webinar platform hosts FEATURED PRESENTATION: Immune Mitigation Strategies to Prevent or Overcome Anti-AAV Abs and Enable AAV-Based Gene Therapy Dosing
Cambridge Innovation Institute webinars
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