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Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey

About This Webinar

Speaker: Aylin Bircan
Affiliation: Sabancı University

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged in Wuhan, and spreadacross the continents, and caused the COVID-19 pandemic. In this talk, I will talk about our recent studywhich focuses on comprehensive genomic analysis of the virus isolates in Turkey. We built aphylogenetic tree with globally obtained 15,277 severe SARS-CoV-2 genomes, and clustered the virusisolates based on the phylogenetic tree and previously annotated classification methods. We performed aphylogenetic analysis of the first thirty SARS-CoV-2 genomes isolated and sequenced in Turkey toidentify specific groups circulating in the country. Our results suggest that the first introduction of thevirus to the country is earlier than the first reported case of infection. Virus genomes isolated from Turkeyare scattered among most types in the phylogenetic tree. Two of the seventeen sub-clusters were foundenriched with the isolates of Turkey, which possibly have spread expansively in the country. Finally, wetraced virus genomes based on their phylogenetic placements. This analysis suggested multipleindependent international introductions of the virus and revealed a hub for the inland transmission.

Who can view: Everyone
Webinar Price: Free
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Webinar hosting presenter ISCB SC RSG Turkey
ISCB RSG Turkey Crew
Webinar hosting presenter
Aylin Bircan received my BSc degree in Chemistry from Koc University in 2012. She worked in Quality Control and Assurance departments of several pharmaceutical companies. In 2018 she received my MSc degree in Computational Biology and Bioinformatics from Kadir Has University. Since 2018 September, she has been a Ph.D. student in Molecular Biology, Genetics and Bioengineering program at Sabanci University. she has been working on phylogenetic analysis of Class C GPCRs under the supervision of Dr. Ogün Adebali.
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BioInfoNet webinar platform hosts Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey
BioinfoNet is an online community for online bioinformatics meetings initiated by ISCB SC RSG Turkey. This meetings include free webinars and paper clubs.
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