Malvern Panalytical Rapid AAV Assays

Jonathan studied Chemistry at the University of Massachusetts Amherst, and joined the Field Application Scientist team at MalvernPanalytical in 2014 after completing his Ph.D. in Chemistry at Purdue University. During his doctoral studies at Purdue, he developed gold nanorod hyperthermia systems for cancer therapy and self-assembled protein nanoparticles for drug delivery. At MalvernPanalytical, Jonathan worked primarily with the Zetasizer and NanoSight product lines in multiple application spaces, from gene therapy, therapeutic proteins, extracellular vesicles, and drug delivery. Over the last six years, Jonathan has been involved in various forms of AAV characterization. From original research in developing novel gold nanoparticle labelling methods to increase the scattering signal of AAV particles, to understanding the strengths and weaknesses of orthogonal analytical assays to measure AAV titer.