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WEBINAR ENDED
· 1 hour

A Platform for Extracellular Interactome Discovery of Immune Receptors

Thursday, June 25, 2020 · 9:00 a.m. · Eastern Time (US & Canada)
About This Webinar

Receptors expressed on the plasma membrane and their interacting partners critically regulate cellular communication during homeostasis and disease, representing main therapeutic targets. Despite its importance in drug development, receptor-ligand proteomics remain a daunting field, partly due to the challenges associated with the study of membrane-expressed proteins. In this webinar, Dr. Bushra Husain will discuss the Conditioned Media AlphaScreen, a new platform for the interrogation of a library consisting of most single transmembrane human proteins. This technology represents a versatile and powerful approach for elucidation of receptor-ligand interactomes, which is essential in understanding basic aspects of plasma membrane protein biology and will ultimately inform the development of novel therapeutic strategies.

Who can view: Everyone
Webinar Price: Free
Webinar ID: c96d88c241db
Featured Presenters
Webinar hosting presenter Azenta Life Sciences
A Brooks Life Sciences Company
GENEWIZ is a leading provider of genomics services to over 4,000 institutional customers worldwide, enabling research scientists to advance their discoveries faster than ever before. A Brooks Life Sciences company, GENEWIZ leads the industry with our unique and proprietary technologies backed by specialized experts in Sanger sequencing, gene synthesis, next generation sequencing, and GLP/CLIA regulatory-compliant services.
Webinar hosting presenter
Senior Scientific Researcher, Genentech Inc.
Bushra Husain received her doctorate in biochemistry at the University of Connecticut, Storrs, studying the mechanism of dimerization and activation of Protein Kinase R in binding viral dsRNAs. Soon after, she joined the Protein Sciences and Screening group at Merck, PA as a senior scientist, and shifted her focus to purification and characterization of challenging multi-pass membrane proteins to support antibody engineering and small molecule screening efforts. She is now part of Genentech’s Receptor Discovery group, whose goal is to identify, characterize, and help modulate novel receptor-ligand or receptor-receptor interactions that are biologically relevant to disease progression, enabling programs within their oncology, cancer immunology, and neuroscience portfolio. She also co-developed and established a robust proximity-based approach to identify unknown human receptor interactions using a miniaturized AlphaScreen assay, and a high coverage library of human single-transmembrane receptors. This is only one of several cutting-edge technologies at the forefront of the receptor-ligand interaction field worldwide developed by their lab to robustly detect challenging membrane protein interactions at high-throughput.
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Azenta Life Sciences webinar platform hosts A Platform for Extracellular Interactome Discovery of Immune Receptors
Azenta Life Sciences Webinars
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